Mr Mann said: “All those 22 names are worthy of investigation by the police.
“The evidence against half of them is very compelling.
“Some of them could definitely be prosecuted and I believe several of them were definitely child abusers.”
The dossier included the names of 13 former ministers.
The probe into the historic sex gang, codenamed Operation Midland, centres on claims of paedophile parties at Dolphin Square, an exclusive block of flats in Pimlico, central London, which has long been popular with MPs because of its proximity to the Houses of Parliament.
The senior officer leading the inquiry said people who lived or visited Dolphin Square in the 1970s “will have seen or heard something that they only understand the significance of now”.
A witness who has played a critical role in the inquiry so far, known only as “Nick”, is understood to have told detectives he saw a Conservative MP strangle a 12-year-old boy to death at an orgy in around 1980.
Detectives have described Nick’s wider evidence about the paedophile ring as “credible and true”.
The police’s decision to go public with the claims is likely to mean they have been able to secure some corroborating evidence surrounding Nick’s claims.
But their appeal for other victims to come forward, as well as other potential witnesses, means detectives are likely to need further first-hand testimony before moving to interview public figures.